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Common Brand Name(s)
Bupropion HCL, Generic Wellbutrin
Uses
Wellbutrin (Anti Depressant) Bupropion (the generic
name of Wellbutrin) is a pharmaceutical prescription
antidepressant which acts directly on the brain
and other nerve cells. It is also used to treat
ADHD (Attention Deficit Disorder), Bipolar depression,
chronic fatigue syndrome, cocaine addiction, nicotine
addiction, and lower back pain. Also, aids in
quitting smoking (identical to Zyban). It is chemically
unrelated to tricyclic, tetracyclic, selective
serotonin re-uptake inhibitor, or other known
antidepressant agents.
How to Use
This medication may be taken with food if stomach
upset occurs. Take doses at regularly scheduled
times each day. Do not take more or less medication
than prescribed and follow your doctor's instructions
carefully. Taking more than the recommended dose
of bupropion will increase your risk of having
a seizure. Do not stop taking this medication
without notifying your doctor. Since this drug
may cause sleeplessness at first, it is best not
to take this near bedtime. It may take 4 weeks
or more before the full effects of this medication
are noticed.
Side Effects
This medication is generally well tolerated. Dry
mouth, headache, increased sweating, nausea/vomiting,
constipation, anxiety, fatigue and blurred vision
may occur. If these effects persist or worsen,
notify your doctor. Report promptly: unusual weight
loss or gain, palpitations, agitation, trouble
sleeping. Unlikely but report promptly: tremor,
dizziness, fainting, mood changes, slowed movements,
difficulty urinating, decreased sex drive, drowsiness.
Very unlikely but report promptly: seizures, mental
problems, fever, muscle aches, yellowing of the
eyes or skin. In the unlikely event you have an
allergic reaction to this drug, seek medical attention
immediately. Symptoms may include trouble breathing,
rash, itching, swelling, or severe dizziness.
If you notice other effects not listed above,
contact your doctor or pharmacist.
Precautions
Before taking bupropion, tell your doctor if you
have: history of seizures or head injury or brain
tumor, heart disease, liver or kidney disease,
eating disorder, diabetes, alcohol dependence,
any allergies, the intent to quit smoking. Because
of the possibility this drug will make you dizzy
and affect coordination, do not drive or operate
machinery until you get used to the drug's effects.
Limit or avoid consumption of alcoholic beverages;
alcohol can increase your risk of seizures. Chronic
alcohol users who suddenly stop the intake of
alcohol while taking bupropion may increase the
risk of having seizures. Suddenly stopping certain
tranquilizers (e.g., diazepam, chlordiazepoxide)
is not recommended because doing so may increase
the risk of having seizures. Elderly patients
may be more sensitive to the effects of this drug.
Tell your doctor if you are pregnant or plan to
become pregnant before taking this drug. This
drug passes into breast milk. Because of the potential
risk to the infant, breast-feeding while using
this drug is not recommended. Consult your doctor
before breast-feeding.
Drug Interactions
Before taking bupropion tell your doctor of all
nonprescription and prescription medications you
may use especially: MAO inhibitors (e.g., isocarboxazid,
phenelzine, tranylcypromine, pargyline, selegiline,
linezolid, furazolidone), levodopa, ritonavir,
corticosteroids (e.g. prednisone), sedatives,
adrenaline-like stimulants (e.g., ephedrine),
products containing nicotine (e.g., patches or
gum). Also report use of drugs which might increase
seizure risk (decrease seizure threshold) such
as: phenothiazines (e.g., chlorpromazine), tricyclic
antidepressants (e.g., amitriptyline), isoniazid
(INH), theophylline. Excess caffeine intake can
increase the chance of seizures with this drug.
Check all nonprescription/prescription drug labels
for caffeine. Consult your doctor or pharmacist.
A certain product used to help quit smoking contains
bupropion. Do not take that product while using
this one. Do not start or stop any medicine without
doctor or pharmacist approval.
Overdose
If overdose is suspected, contact your local poison
control center or emergency room immediately.
Symptoms of overdose may include seizures, hallucinations,
rapid heart rate, and loss of consciousness.
Notes
Do not allow anyone else to take this medication.
Missed Dose
Take any missed dose as soon as possible but not
if it is within 4 hours of the next dose. If it
is time for the next dose, skip the missed dose
and resume your regular schedule. Do not "double-up"
the dose.
Storage
Store at room temperature and keep away from moisture
and sunlight. Do not store in the bathroom.
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